Excess intake of which vitamin can lead to the formation of oxalate stones?

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Excess intake of ascorbic acid, commonly known as Vitamin C, can lead to the formation of oxalate stones. This occurs because high doses of Vitamin C can be metabolized into oxalate in the body. When the concentration of oxalate increases, it can combine with calcium, resulting in the precipitation of calcium oxalate stones in the kidneys.

While Vitamin D affects calcium metabolism and could hypothetically influence stone formation through calcium levels, it is not directly linked to an increase in oxalate levels. Vitamins E and K do not play a role in oxalate metabolism, which further distinguishes ascorbic acid as the vitamin that is particularly associated with oxalate stone formation. Therefore, excessive intake of Vitamin C is the primary concern when discussing the risk factors for oxalate kidney stones.

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