In addition to Doxycycline, which medication should be given for gonorrhea coinfection?

Ceftriaxone is the appropriate medication to administer for gonorrhea coinfection when treating with Doxycycline, particularly if the patient is suspected of having chlamydial infection as well. Gonorrhea is caused by Neisseria gonorrhoeae, which has developed resistance to several antibiotics over the years. Ceftriaxone is a third-generation cephalosporin that remains highly effective against this organism.

In the typical treatment regimen for sexually transmitted infections, particularly when coinfection with Chlamydia trachomatis is also possible, Doxycycline is often used to cover Chlamydia, while Ceftriaxone effectively addresses gonorrhea. This dual therapy approach is in line with the current treatment guidelines, which recommend combining effective agents to combat potential resistant strains of gonorrhea and ensure comprehensive coverage of both infections.

Other medications listed do not serve the same purpose in this context. Azithromycin, while previously used as a single agent for Chlamydia and sometimes administered in the past for dual therapy, is not recommended as a standalone treatment for gonorrhea due to rising resistance. Metronidazole is typically used for anaerobic infections and is not indicated for either gonorrhea or chlamydial infections