In AIDS patients, pulmonary presentations associated with co-infection are typically attributed to which virus?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

In patients with AIDS, one of the most common pulmonary presentations associated with opportunistic infections is attributed to Cytomegalovirus (CMV). CMV is a member of the herpesvirus family and its infections can lead to severe complications in individuals with compromised immune systems, such as those with HIV/AIDS.

In the context of AIDS, patients often experience reactivation of latent infections due to their weakened immune response. CMV can cause a variety of pulmonary problems, including pneumonitis, which presents with respiratory symptoms such as cough, difficulty breathing, and hypoxemia. The presence of opportunistic pathogens like CMV highlights the importance of immune status in the development and severity of respiratory infections in these patients.

While other viruses like RSV, Influenza, and Parainfluenza can certainly affect the respiratory system, they are typically more commonly associated with infections in individuals who are not immunocompromised. Therefore, CMV is particularly significant in the context of AIDS-related pulmonary disease.

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