In conjunction with which age group is Chronic Myeloid Leukemia (CML) commonly diagnosed?

Chronic Myeloid Leukemia (CML) is primarily diagnosed in adults, particularly between the ages of 30 and 60. This age range reflects the typical demographic for CML, as it is rare in younger populations and less commonly seen in the elderly. The median age at diagnosis for CML is around 55 years old, indicating that it most often presents in middle-aged adults. This occurrence is associated with genetic mutations, particularly the Philadelphia chromosome, which are more prevalent in this specific age group.

In contrast, CML is not commonly diagnosed in children, adolescents, or individuals over 70 years of age, where other forms of leukemia or hematological disorders may be found more frequently. Thus, the age group of 30-60 aligns closely with the typical clinical presentations, treatment considerations, and underlying pathophysiology associated with CML.