Intranuclear eosinophilic droplet-like bodies are associated with which viral infection?

Intranuclear eosinophilic droplet-like bodies are characteristically associated with viral infections like herpes simplex virus (HSV) and cytomegalovirus (CMV). These eosinophilic bodies represent viral inclusions where the virus replicates within the host cell's nucleus, leading to distinctive pathological findings upon histological examination.

In the case of HSV, these droplet-like inclusions can appear early in the infection as the virus causes cellular changes in the infected tissue. For CMV, similar intranuclear inclusions are also observed, which are often referred to as “owl-eye” inclusions due to their appearance.

Other options, such as HIV or hepatitis viruses, do not typically show this specific kind of pathology. Influenza is primarily associated with cytoplasmic changes rather than pronounced nuclear alterations. Thus, identifying intranuclear eosinophilic droplet-like bodies serves as an important histopathological marker for diagnosing infections caused by HSV or CMV.