What age-dependent change affects the respiratory system similar to obstructive lung disease?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

The correct answer highlights the age-dependent change in the respiratory system characterized by decreased elasticity, which can be likened to the features of obstructive lung disease, specifically referred to in this context as senile emphysema.

As individuals age, the elastic recoil of the lungs diminishes. This loss of elasticity contributes to an increase in lung volume but can also lead to incomplete emptying of the lungs, mimicking the obstructive patterns seen in conditions like chronic obstructive pulmonary disease (COPD). In obstructive lung disease, airflow limitation is primarily due to the narrowing of airways, where the increased compliance and decreased elastic recoil appear similar.

In contrast, the other options do not represent age-related changes that would parallel obstructive lung disease. An increase in FEV1 is not consistent with age-related lung changes, as typically both FEV1 and FEV1/FVC ratios decline with age. An increase in arterial oxygen levels (PaO2) is also not a typical age-related change; rather, oxygen exchange may become less efficient. Improved airflow rates would suggest a positive change in lung function, but with aging and loss of elastic recoil, airflow typically decreases. Thus, the decreased elasticity seen in aging provides a clear parallel to the decreased

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