What class of drugs is indicated for the treatment of vaso-receptor antagonism in SIADH?

The class of drugs indicated for the treatment of vaso-receptor antagonism in Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH) is the -vaptan drugs. Vaptans, such as tolvaptan and conivaptan, specifically act as vasopressin receptor antagonists. They work by blocking the action of antidiuretic hormone (ADH) at the V2 receptors in the kidney, leading to increased free water excretion (aquaresis) and dilution of excess serum sodium level, which is particularly beneficial in managing the hyponatremia associated with SIADH.

This mechanism is essential because in SIADH, there is an inappropriate secretion of ADH, which promotes water retention and results in low serum sodium levels. By using vaptans, the adverse effects of excess ADH can be counteracted, restoring the fluid and electrolyte balance. Other options listed do not have this specific action or indication in treating SIADH.