What commonly presents with tricuspid regurgitation?

Tricuspid regurgitation often occurs in the context of conditions that affect the right side of the heart or cause increased pressure in the right heart chambers. Pulmonary hypertension is a primary condition that can lead to tricuspid regurgitation. When the pressure in the pulmonary arteries is elevated, it puts strain on the right ventricle, which may result in right ventricular dilation and, consequently, the failure of the tricuspid valve to close completely during ventricular contraction. The increased right ventricular volume leads to regurgitant flow back into the right atrium, manifesting as tricuspid regurgitation.

The other conditions listed do not directly lead to tricuspid regurgitation in the same way. Mitral valve prolapse primarily affects the left side of the heart, while aortic stenosis and left ventricular hypertrophy are also conditions influenced by pressure overload on the left ventricle. These conditions do not typically cause changes that would directly impact the tricuspid valve. Therefore, pulmonary hypertension stands out as the condition most commonly associated with the development of tricuspid regurgitation due to the hemodynamic consequences it imposes on the heart.