What condition is indicated by a neonate presenting with arm paralysis following a difficult birth?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

The presentation of arm paralysis in a neonate following a difficult birth is most consistent with Erb-Duchenne palsy. This condition typically occurs due to injury to the upper trunk of the brachial plexus, which can happen during a difficult delivery, particularly in situations such as shoulder dystocia. The specific nerves affected include the C5 and C6 roots, which are responsible for motor function in the shoulder and arm.

Clinical features of Erb-Duchenne palsy include weakness or paralysis of the upper arm muscles, leading to the typical "waiter's tip" posture where the arm is adducted and internally rotated. The affected infant may have limited movement of the affected arm and may show a decreased grasp reflex on that side.

The other options, while they may involve arm paralysis, are characterized by different clinical presentations or mechanisms of injury. Klumpke's palsy involves lower trunk injury to the brachial plexus (C8 and T1) and affects the hand and forearm, presenting differently than Erb-Duchenne palsy. Brachial plexus avulsion indicates a more severe injury where the plexus is torn from the spinal cord, often resulting in greater disability. Spinal cord injury can result

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