What condition is linked to deficiencies of copper?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

Copper deficiency is linked to microcytic anemia due to its critical role in the production and maturation of red blood cells. Copper is a cofactor for several enzymes, including ceruloplasmin, which is involved in iron metabolism. Without adequate copper, iron is not effectively mobilized within the body, leading to impaired hemoglobin synthesis. This can result in the development of microcytic anemia, characterized by smaller-than-normal red blood cells and low hemoglobin levels.

While options like hyperthyroidism, scurvy, and osteoporosis involve various nutritional factors and mechanisms, they are not directly associated with copper deficiency. Hyperthyroidism relates mainly to excess thyroid hormone production, scurvy is caused by a deficiency in vitamin C, and osteoporosis is typically associated with calcium and vitamin D deficiencies, along with other factors such as hormonal levels and physical activity.

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