What is the first-line treatment for generalized anxiety disorder?

The first-line treatment for generalized anxiety disorder (GAD) is typically the selective serotonin reuptake inhibitors (SSRIs). SSRIs, such as sertraline, escitalopram, and paroxetine, are effective in managing the symptoms of anxiety and are considered first-line pharmacotherapy due to their favorable safety profile and efficacy.

While buspirone is an anxiolytic medication that can be used for GAD, it is not generally considered the first-line treatment. It may take several weeks to achieve its therapeutic effects, which makes it less preferred for immediate symptom relief compared to SSRIs.

Benzodiazepines can provide short-term relief of anxiety symptoms, but they are not recommended as a first-line treatment due to concerns about dependence, tolerance, and withdrawal issues with long-term use.

Cognitive behavioral therapy (CBT) is a highly effective non-pharmacological treatment for GAD and may be used alone or in combination with medications. However, in the context of first-line treatments, SSRIs have a stronger evidence base and are often preferred for initial pharmacological management.

In summary, SSRIs are typically the standard first-line treatment due to their effectiveness and safety in managing generalized anxiety disorder, whereas other options like buspirone or