What is the treatment for Strongyloides stercoralis infection?

The treatment for Strongyloides stercoralis infection is ivermectin, which is a potent anthelmintic medication specifically effective against this parasitic infection. Ivermectin works by binding to glutamate-gated chloride channels in the worms, leading to paralysis and eventual death of the parasite. This makes it a first-line treatment option for strongyloidiasis, including both acute and chronic infections.

In contrast, other commonly suggested treatments do not target Strongyloides effectively. Praziquantel primarily treats trematode and cestode infections (like schistosomiasis and certain tapeworms) rather than Strongyloides. Metronidazole is effective against anaerobic bacteria and certain protozoa but does not effectively treat helminth infections such as strongyloidiasis. Cyclophosphamide is a chemotherapeutic agent and immunosuppressant, which does not have any action against parasitic infections.

Thus, when considering the most effective treatment for Strongyloides stercoralis, ivermectin stands out as the appropriate choice, aligning with current medical guidelines for managing this specific infection.