What is the typical age range for patients diagnosed with Acute Myeloid Leukemia (AML)?

Acute Myeloid Leukemia (AML) is most commonly diagnosed in older adults, with the median age at diagnosis being around 60 years. This age distribution is significant because the incidence of AML increases with age, and it is relatively rare in children and adolescents.

The pathology of AML originates in the myeloid line of blood cells and is characterized by rapid proliferation of abnormal myeloblasts. While there are rare forms of leukemia that can occur in younger populations, AML predominantly manifests in adults, particularly those in their 60s and above due to a combination of genetic factors, environmental exposures, and the cumulative effects of aging on the hematopoietic system.

Focusing on the other options, AML is much less common in childhood, which is shown by option A. The frequency of diagnosis in younger adults, like those in the 30-50 age range, noted in option C, is comparatively lower since leukemia types such as Acute Lymphoblastic Leukemia (ALL) tend to be more prevalent in that demographic. Lastly, while there are cases diagnosed in older adults over 70, this group represents an even higher-risk population usually diagnosed with more advanced presentations, thus not reflecting the typical age range for initial diagnosis.