What kind of necrosis is primarily seen in acute glomerulonephritis?

In acute glomerulonephritis, the type of necrosis that is primarily observed is fibrinoid necrosis. This specific form of necrosis is characterized by the deposition of fibrin-like proteinaceous materials within the walls of blood vessels and tissues. In the context of glomerulonephritis, this necrosis occurs as a result of immune complex deposition and the subsequent inflammatory response, leading to vascular damage and an altered structure of the glomeruli.

Fibrinoid necrosis is significant in this condition because it reflects the underlying pathology associated with the inflammatory processes that occur as a result of various causes of glomerulonephritis, such as autoimmune disorders or infections. The presence of fibrin and immune complexes in the glomeruli can lead to impaired kidney function.

Other types of necrosis, such as coagulative, caseous, and liquefactive necrosis, have distinct characteristics and are typically associated with different pathological processes. For example, coagulative necrosis is often seen in myocardial infarction; caseous necrosis is associated with tuberculosis infections; and liquefactive necrosis is commonly observed in brain tissue following a stroke. Therefore, while these other forms of necrosis have their own specific contexts, fibrino