What neurological condition is indicated by toe extension and fanning upon plantar scrape?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

The presence of toe extension and fanning upon plantar scrape is indicative of the Babinski sign, which reflects an upper motor neuron lesion in the corticospinal tract. Normally, stimulation of the sole of the foot leads to flexion of the toes in adults; however, in the presence of an upper motor neuron lesion, the response changes, resulting in toe extension and fanning. This reflex is particularly important in assessing neurological function and can be seen in various conditions that affect the central nervous system, such as a stroke, multiple sclerosis, or spinal cord injury.

Understanding the mechanics of the Babinski sign provides insight into the integrity of the corticospinal pathways. In infants, the Babinski sign is a normal finding due to the immaturity of the nervous system. However, in adults, its presence suggests a disruption of normal neural pathways, which is significant in diagnosing certain neurological disorders. This sign serves as a clinical tool for neurologists to identify potential dysfunction in upper motor neuron control.

In comparison to the other options presented, the Babinski sign is directly linked to the neurological response observed in this scenario, making it the definitive choice for toe extension and fanning upon plantar stimulation. Other conditions listed, such as Multiple Sclerosis, Peripheral Neuropathy

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