What organism is commonly associated with "red currant jelly" sputum in alcoholic or diabetic patients?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

The organism commonly associated with "red currant jelly" sputum in alcoholic or diabetic patients is Klebsiella pneumoniae. This classic presentation refers to the thick, mucoid sputum that can be seen in severe cases of pneumonia caused by this bacterium. Klebsiella pneumoniae is a gram-negative bacillus that is often part of the normal flora of the intestines, but it can cause opportunistic infections, particularly in individuals with compromised immune systems or underlying health conditions such as alcoholism or diabetes.

In these patients, Klebsiella pneumoniae can lead to a range of pulmonary complications, including necrotizing pneumonia and lung abscesses. The characteristic "red currant jelly" appearance of the sputum is due to the presence of blood and necrotic tissue, which can result from the extensive tissue destruction caused by the infection. This feature, combined with the patient's background of alcoholism or diabetes, makes Klebsiella pneumoniae a significant consideration in the differential diagnosis of pneumonia in these populations.

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