What type of gastric ulcer is typically associated with CNS injury?

Cushing's ulcer is specifically associated with central nervous system (CNS) injury, which can include conditions like head trauma, brain surgery, or increased intracranial pressure. This type of ulcer is a result of increased vagal stimulation due to CNS lesions, leading to increased gastric acid secretion.

The pathophysiology involves the overstimulation of gastric acid production, which can cause mucosal damage and contribute to ulcer formation. Cushing's ulcers typically present as single ulcers in the stomach or proximal duodenum, and they may be more likely to perforate due to their often deeper nature compared to other ulcers.

Understanding this connection between CNS injury and the development of Cushing's ulcers is crucial, as it highlights the broader implications of brain injuries on gastrointestinal health, particularly in clinical settings where patients may be unconscious or otherwise unable to communicate symptoms.