What type of genital lesion is nonpainful and associated with l syphilis?

The genital lesion that is nonpainful and associated with primary syphilis is known as a chancre. A chancre typically appears as a solitary, firm, round sore at the site of Treponema pallidum infection, which is the causative agent of syphilis. This lesion is usually painless and develops about three weeks after exposure to the bacterium.

In contrast, conditions like chancroid present as painful ulcers, often accompanied by swollen lymph nodes; herpes simplex infections usually present with painful vesicular lesions; and condyloma acuminatum, caused by human papillomavirus (HPV), results in warty lesions that can also be painless but are distinctly different from the chancre of syphilis. The key characteristics of a chancre—the nature of its pain levels, the time frame of its appearance, and its association with primary syphilis—clearly distinguish it from other genital lesions described in the options.