What type of lymphoma typically has a high cell turnover rate and quick progression?

Diffuse large B-cell lymphoma (DLBCL) is characterized by a high cell turnover rate and rapid progression. This is a type of non-Hodgkin lymphoma that is often aggressive, leading to a rapid increase in size of lymph nodes or other involved tissues. The pathophysiology of DLBCL involves the proliferation of large B-cells that can quickly overwhelm the immune system and result in significant symptoms, such as fever, night sweats, and weight loss.

Patients with DLBCL may present with an advanced stage of disease at diagnosis, and the disease frequently requires prompt intervention. The aggressive nature of this lymphoma means that it typically necessitates immediate treatment, which can include intensive chemotherapy, and sometimes targeted therapies depending on specific genetic markers.

In contrast, other types of lymphoma mentioned do not share the same rapid course. Follicular lymphoma, for example, generally has a more indolent course and can often be managed over a longer period. Mantle cell lymphoma has an intermediate to high aggressiveness, but it is not as rapidly progressive as DLBCL. Hodgkin lymphoma is also treated differently and may have varying rates of progression, but DLBCL is still recognized for its particularly brisk clinical course. Thus, diffuse large B