What type of skin lesions are associated with porphyria cutanea tarda?

Porphyria cutanea tarda (PCT) is primarily associated with skin lesions characterized by vesicles and bullae. This condition results from a deficiency in the enzyme uroporphyrinogen decarboxylase, which leads to an accumulation of porphyrins, especially in the skin. Sun exposure triggers the release of these porphyrins, leading to the development of fragile skin that is prone to blistering upon relatively minor trauma or sun exposure.

The vesicular and bullous lesions are typically seen on sun-exposed areas of the skin, such as the hands and face. Over time, repeated injury and healing can lead to scarring and changes in skin pigmentation. Understanding the pathophysiological mechanisms behind PCT helps emphasize the importance of sun protection and early recognition of the skin manifestations that characterize this disorder.

Other options, while related to different dermatological conditions, do not align with the specific lesions associated with porphyria cutanea tarda. For instance, coarse basophilic stippling pertains to a hemoglobin synthesis issue often seen in lead poisoning rather than a skin condition. Ulcerative lesions and scaly patches can be seen in a variety of dermatological conditions but are not specific to PCT. Instead, the hallmark ves