What type of tumor is associated with c-myc activation and EBV in the context of "starry sky" histology?

Burkitt's lymphoma is characterized by a unique histopathological appearance described as "starry sky" due to a high proliferation of B cells and interspersed macrophages. This pattern arises from the rapid turnover and cell death of tumor cells, which are extensively infiltrated by macrophages that consume cellular debris.

C-myc activation plays a crucial role in the pathogenesis of Burkitt's lymphoma, often occurring due to translocation events such as t(8;14). This genetic alteration leads to the overexpression of the c-myc oncogene, driving proliferation in B cells. Moreover, Epstein-Barr virus (EBV) is frequently associated with Burkitt's lymphoma, contributing to the oncogenic process and affecting the immune response to the tumor.

In contrast, other lymphomas listed do not have the specific combination of c-myc activation, EBV association, and the distinct histological finding of "starry sky." Hodgkin's lymphoma is characterized by Reed-Sternberg cells and a different histological pattern. Diffuse large B-cell lymphoma shows a markedly different growth pattern without the same "starry sky" appearance. Finally, follicular lymphoma has its own distinct genetic and histological features, primarily arising from trans