Which agent is used in the treatment of sporotrichosis?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

In the treatment of sporotrichosis, the correct agent is not oral potassium chloride, but rather itraconazole or, in some cases, potassium iodide. Sporotrichosis is a fungal infection caused by Sporothrix schenckii, typically acquired through traumatic inoculation from contaminated plant material, like rose thorns.

Potassium iodide, while not mentioned in the options, is one of the traditional treatments for sporotrichosis. It acts as an antifungal agent by enhancing the immune response to the fungus. In more recent practices, itraconazole has become the preferred choice due to its effectiveness and safety profile.

Oral potassium chloride, which is primarily used to treat or prevent potassium deficiency, does not have a role in treating fungal infections. Dexamethasone is a corticosteroid that reduces inflammation and suppresses the immune system but does not have antifungal properties. Valproate is an anticonvulsant medication and also does not provide any benefit in the treatment of sporotrichosis.

Effective management of sporotrichosis requires antifungal therapy, with options like itraconazole or potassium iodide being the correct approaches, reaffirming that the correct treatment is not among the listed options.

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