Which agents are used in the treatment of Clostridium tetani infections?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

The treatment of Clostridium tetani infections involves a combination of strategies to neutralize the toxin produced by the bacteria, prevent further illness, and manage symptoms. Administering tetanus antitoxin is crucial as it helps to neutralize the circulating tetanospasmin toxin. A booster of the tetanus vaccine is also necessary for immunization and to enhance the body's defense against the toxin, especially if the patient's vaccination status is not up to date.

Diazepam, a muscle relaxant, is frequently used to reduce the severe muscle spasms and rigidity that occur with tetanus infection, further aiding in symptom management and providing comfort to the patient.

Together, these components—antitoxin therapy to block the effects of the toxin, a vaccine booster to support long-term immunity, and diazepam for muscle relaxation—form a comprehensive approach to treating tetanus infections. Other options might not include these critical aspects of care, making this combination the most effective treatment.

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