Which bacteria are characterized by branching gram-positive rods and sulfur granules?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

The correct response highlights Actinomycetes because these are the bacteria known for their branching, filamentous structures and the presence of sulfur granules. Actinomycetes, particularly the genus Actinomyces, are often linked with human infections, such as actinomycosis, which can manifest as chronic granulomatous lesions. The sulfur granules, which are yellowish clumps, are part of the characteristic pathology associated with Actinomyces infections, often seen in abscesses.

In addition to their branching morphology, Actinomycetes are also classified as gram-positive. Understanding their morphology and growth patterns is crucial in microbiology and pathology as it helps in distinguishing them from other organisms.

While Nocardia species are also gram-positive and exhibit branching, they more commonly stain weakly gram-positive and are notable for their association with pulmonary infections and opportunistic infections, especially in immunocompromised patients. However, they are not typically associated with sulfur granules. On the other hand, Staphylococcus aureus is a grape-like cluster of cocci and does not exhibit branching or sulfur granules, and Mycobacterium tuberculosis is recognized for its staining characteristics (acid-fast) and associated primarily with tuberculosis, lacking the filament

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