Which bacteria is sensitive to novobiocin?

Staphylococcus epidermidis is sensitive to novobiocin, which is a key characteristic that helps differentiate it from other Staphylococci, particularly Staphylococcus saprophyticus. This distinction is important in clinical microbiology, especially in the context of urinary tract infections, where Staphylococcus saprophyticus is a common pathogen and typically resistant to novobiocin.

When identifying Staphylococcus species in the laboratory, the novobiocin sensitivity test is a quick and effective way to ascertain the identity of the organism. Staphylococcus epidermidis, often considered a coagulase-negative Staphylococcus (CoNS), is generally found to be sensitive to novobiocin, making it a reliable marker for differentiating CoNS in various clinical settings.

In contrast, other choices such as Staphylococcus aureus and Streptococcus pneumoniae are not relevant regarding novobiocin sensitivity, as this test is specifically used in the context of Staphylococci. Therefore, recognizing that Staphylococcus epidermidis is sensitive to novobiocin is essential for effective clinical decision-making and microbiological diagnosis.