Which cancer type is associated with elevated levels of LDH?

Hodgkin's lymphoma is known to be associated with elevated levels of lactate dehydrogenase (LDH). LDH is an enzyme found in nearly all body tissues, and elevated levels can indicate tissue damage or cell turnover, which is common in many cancers. In Hodgkin's lymphoma, high LDH levels reflect a more aggressive disease and are considered a marker of poor prognosis. Increased LDH levels in this context are attributed to the rapid proliferation of tumor cells and the destruction of normal tissue, resulting in the release of LDH into the bloodstream. Therefore, monitoring LDH can provide valuable information about the disease's activity and progression in patients with Hodgkin's lymphoma.

While LDH can also be elevated in other malignancies and conditions, it is specifically recognized and studied as a key marker in Hodgkin's lymphoma, solidifying its association with this type of cancer.