Which condition is indicated by a red, itchy, and swollen rash of the nipple and areola?

Paget's disease of the breast is characterized by a specific presentation of the nipple and areola, typically manifesting as a red, itchy, and swollen rash. This condition is a form of breast cancer that often involves the skin of the nipple and is associated with underlying ductal carcinoma in situ or invasive breast carcinoma. The dermatitis-like changes and symptoms are due to the spread of cancerous cells along the ducts of the breast, leading to the alteration in skin appearance and sensation.

The uniqueness of Paget's disease lies in the combination of the rash, itching, and swelling localized to the nipple and areolar area. These symptoms can lead to misdiagnosis as eczema or dermatitis, but the key distinguishing factor is the underlying malignancy that often accompanies Paget's, necessitating further investigation if such symptoms occur.

In contrast, intraductal papilloma typically presents with nipple discharge rather than a rash, while breast carcinoma could present in many forms, including a mass or puckering but is not specifically characterized by the rash on the nipple and areola. Allergic dermatitis may cause an itchy red rash but is generally more diffuse and not limited to the nipple area specifically. Thus, the distinct patterns and manifestations seen in Paget's disease make it