Which lymphoma is characterized by a high proliferation rate and is often associated with HIV?

Burkitt's lymphoma is characterized by a high proliferation rate and is notably linked to HIV infection. This aggressive form of non-Hodgkin lymphoma is associated with the translocation of the MYC oncogene, leading to increased cell division and rapid tumor growth.

Burkitt's lymphoma often presents in immunocompromised patients, such as those with HIV, due to the weakened immune system's inability to control proliferative B-cell lymphomas. The disease can manifest in various sites but is most commonly seen in the abdominal region or as a jaw lesion in children.

While follicular lymphoma and non-Hodgkin lymphoma encompass a broader range of lymphomas and can include indolent forms, they do not exhibit the same proliferation rate as Burkitt's lymphoma. Chronic lymphocytic leukemia, however, is a type of leukemia that predominantly affects older adults and is characterized by a different pathophysiology and proliferation rate. Therefore, Burkitt's lymphoma stands out in this context due to its distinctive high rate of growth and association with immunocompromised states like HIV.