Which medication is commonly used to treat benign prostatic hyperplasia?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

Benign prostatic hyperplasia (BPH) is a common condition in older men characterized by the enlargement of the prostate gland, leading to urinary obstruction and other symptoms. The treatment options for BPH typically include medications that help alleviate symptoms or reduce the size of the prostate.

Tamsulosin is an alpha-1 adrenergic antagonist that works by relaxing the smooth muscles in the prostate and bladder neck, which helps to improve urine flow and relieve symptoms associated with BPH. This rapid improvement in urinary symptoms makes Tamsulosin one of the first-line treatments for managing BPH.

Finasteride is a 5-alpha reductase inhibitor that reduces the size of the prostate over time by blocking the conversion of testosterone to dihydrotestosterone (DHT), a hormone that promotes prostate growth. While it may take several months to achieve a significant reduction in symptoms, it is effective for long-term management of BPH, especially in men with larger prostates.

Both of these medications (Tamsulosin and Finasteride) are commonly used in the management of BPH, often in conjunction to maximize their therapeutic effects. Tamsulosin addresses symptoms quickly, while Finasteride provides a more gradual reduction in prostate size and symptom relief

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