Which of the following is a function inhibited by ANP?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

Atrial natriuretic peptide (ANP) is a hormone produced by the atria of the heart that plays a crucial role in regulating blood pressure and volume. One of its key functions is to promote natriuresis, which is the excretion of sodium through the urine, leading to a decrease in blood volume and, consequently, a reduction in blood pressure.

ANP inhibits aldosterone release from the adrenal cortex. Aldosterone usually promotes sodium reabsorption in the kidneys, which increases blood volume and pressure. By inhibiting aldosterone release, ANP counteracts the effects of other hormones that contribute to fluid retention, thus helping to maintain homeostasis and regulate cardiovascular function.

While ANP affects various aspects of renal and cardiovascular physiology, its primary function in this context is related to the inhibition of aldosterone production, making this the correct choice.

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