Which of the following is NOT a cancer associated with an oncogenic virus based on the provided information?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

Prostate adenocarcinoma is considered the option that is not associated with an oncogenic virus. Most cancers associated with oncogenic viruses have established viral links with specific types of malignancies. For example, adult T-cell leukemia/lymphoma is linked to Human T-cell lymphotropic virus (HTLV-1), while CNS malignant lymphoma has strong associations with Epstein-Barr virus (EBV), particularly in immunocompromised individuals. Hairy cell leukemia, although somewhat less common, does have associations with viral infections, but it is not principally linked to an oncogenic virus in the same way as the previously mentioned conditions.

In contrast, prostate adenocarcinoma does not have a recognized causative association with any viral infection. Its etiology is more strongly linked to hormonal influences and genetic predispositions rather than viral oncogenesis. This distinction underscores the importance of understanding the specific mechanisms by which certain viruses contribute to tumorigenesis, contrasting with the multifactorial causes of other cancers, such as prostate cancer.

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