Which primary cardiac tumor is most common in adults?

Prepare for USMLE Step 1 Pathology Exam with comprehensive quizzes, flashcards, and detailed explanations. Enhance your understanding and be exam-ready!

Myxoma is recognized as the most common primary cardiac tumor in adults. It is typically found in the left atrium and is often associated with a characteristic "ball valve" effect, where the tumor may obstruct blood flow through the heart. Myxomas are composed of a mix of tissue types, including stellate or spindle-shaped cells within a myxoid (mucoid) stroma, making them unique in appearance and histology.

The clinical presentation of myxoma can vary; many patients may be asymptomatic, while others can experience symptoms such as dyspnea, constitutional symptoms (like fever or malaise), or signs of obstruction. Myxomas are also known to have an association with a genetic condition called Carney complex, which can predispose individuals to multiple myxomas and other tumors.

Other tumors mentioned, such as rhabdomyoma, fibroma, and angiosarcoma, are less common among adults. Rhabdomyomas, for instance, primarily occur in children and are associated with tuberous sclerosis. Fibromas, while seen in the heart, are relatively rare and more commonly found in other tissues. Angiosarcomas are aggressive malignancies, but their incidence is lower compared

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