Which subtype of cervical carcinoma is most commonly associated with HPV infection?

Squamous cell carcinoma is the subtype of cervical carcinoma most commonly associated with human papillomavirus (HPV) infection, particularly HPV types 16 and 18. HPV is a well-established causative agent in the pathogenesis of cervical cancer, and squamous cell carcinoma represents the predominant type, accounting for approximately 70-90% of cervical cancer cases globally.

This association is crucial for understanding the disease's epidemiology and for implementing preventive measures such as HPV vaccination and screening programs. While other types such as adenocarcinoma do have links to HPV, the correlation is not as strong or as prevalent as with squamous cell carcinoma. Thus, recognizing the primary role of HPV in the development of squamous cell carcinoma provides essential insight into cervical cancer prevention and management strategies.