Which symptoms are indicative of riboflavin (B2) deficiency?

Riboflavin (vitamin B2) deficiency is characterized by specific symptoms related to mucocutaneous tissues. The hallmark symptoms include glossitis (inflammation of the tongue), stomatitis (inflammation of the mucous membranes of the mouth), and cheilosis (cracks or sores on the lips). These manifestations occur because riboflavin plays a critical role in energy metabolism and the maintenance of healthy epithelial tissues.

In contrast, the symptoms associated with the other options are related to different vitamin deficiencies. For instance, diarrhea, dermatitis, and dementia are classic manifestations of niacin (vitamin B3) deficiency, known as Pellagra. Night blindness and dry skin are typically linked to vitamin A deficiency. Pellagra symptoms specifically arise from a deficiency of niacin, while the mucosal symptoms listed are directly tied to riboflavin deficiency. Therefore, the symptoms that uniquely point to riboflavin deficiency are glossitis, stomatitis, and cheilosis.