Which syndrome is characterized by hyperphagia, hypersexuality, hyperorality, and hyperdocility due to a bilateral amygdala lesion?

Klüver-Bucy syndrome is characterized by a distinct set of behavioral changes: hyperphagia (increased appetite), hypersexuality, hyperorality (the tendency to examine objects by mouth), and hyperdocility (increased compliance and reduced fear responses). This clinical presentation is typically associated with bilateral lesions of the amygdala, a brain region crucial for emotional processing and behavior regulation.

The amygdala plays a key role in mediating emotions and social behaviors. When its function is disrupted, as in the case of bilateral lesions, the result can be a loss of inhibitions and alterations in behavioral practices, manifesting as the features seen in Kübler-Bucy syndrome.

The other syndromes mentioned involve different pathophysiological mechanisms and symptoms that do not match this particular combination of hyperactive behaviors. For example, Down syndrome is associated with a genetic trisomy affecting physical and cognitive development, Wernicke-Korsakoff syndrome is related to thiamine deficiency leading to confusion and memory issues, and Prader-Willi syndrome, a genetic disorder characterized by insatiable appetite and obesity along with developmental delays, has different behavioral manifestations. Thus, the unique presentation of hyperphagia, hypersexuality, hyperor