Which tumor features cytoplasmic rod-shaped crystalloid of Reinke?

The presence of cytoplasmic rod-shaped crystalloid of Reinke is a characteristic feature of Leydig cell tumors, which are a type of sex-cord stromal tumor found in the testes. These tumors arise from Leydig cells, which are responsible for testosterone production. The crystalloid of Reinke represents degenerative structures within those cells, and they can be visualized histologically.

Leydig cell tumors often present clinically with symptoms related to excess androgen production, such as precocious puberty in children or virilization in adults. They are typically well-circumscribed tumors, and the crystalloid bodies found within them can aid in their diagnosis during pathological examination.

In contrast, Sertoli cell tumors, while related to testicular function, do not feature Reinke crystals and are associated with different pathological findings. Other tumors like embryonal carcinoma and yolk sac tumors belong to different categories of germ cell tumors and do not exhibit these specific crystalloid structures. The presence of Reinke crystals is a distinct histological finding that is pathognomonic for Leydig cell tumors.