Which tumor is not typically associated with elevated levels of AFP?

Alpha-fetoprotein (AFP) is a protein that is typically produced by the fetal liver and is often used as a tumor marker in certain cancers. It is significantly elevated in conditions like hepatocellular carcinoma, germ cell tumors, and endodermal sinus tumors.

Hepatocellular carcinoma, a primary liver cancer, frequently shows elevated AFP levels because liver cells produce this protein, especially when they are malignant.

Germ cell tumors, particularly non-seminomatous types, can also lead to increased AFP levels, as these tumors may originate from cells that produce this protein.

Endodermal sinus tumors, a type of germ cell tumor often found in the testes or ovaries, have a well-known association with elevated AFP levels due to their similar origin of germ cells responsible for AFP production.

In contrast, carcinoma of the lung does not typically lead to elevated AFP levels, as lung cancer is not associated with the production of this protein. While lung cancer may be associated with other tumor markers depending on the histological subtype, AFP is not one of them. Therefore, this option accurately identifies a tumor that is not associated with elevated AFP levels.