Which tumor type is known to secrete Bombesin as a marker?

Neuroblastoma is a tumor that primarily arises in the adrenal glands or sympathetic nervous system and is most commonly found in children. One of the notable secretions associated with neuroblastoma is Bombesin, which is a neuropeptide involved in various physiological functions, including stimulation of gastric acid secretion and modulating gastrointestinal activity. The presence of Bombesin in the context of neuroblastoma serves as a useful diagnostic marker for this tumor type.

The secretion of Bombesin is particularly relevant because it reflects the neuroectodermal origin of neuroblastoma and its differentiation state. In neuroblastoma, the production of neuropeptides such as Bombesin helps in characterizing the tumor and can be utilized in both the diagnosis and in understanding the behavior of the tumor.

In contrast, other listed tumor types such as breast cancer, Hodgkin's lymphoma, and ovarian cancer do not secrete Bombesin as a marker, making them less relevant in this context. Each of these cancers is associated with different tumor markers and secretory profiles that do not include Bombesin, affirming the specificity of neuroblastoma for this marker.